In many cases, swelling in one leg can also be caused by arthritis in the knee joint or the ankle. calves or thighs. However, blood clots in the knee or infections in the leg can also cause edema. Swollen calf can be caused by three categories of conditions - natural, traumatic, and systemic issues. Edema is also a sign of thrombosis due to slow-flowing blood, which can cause a blood clot. Most often, it’s the first two causes, which we will go further in detail below but if you just had a long plane ride or sat down for a long time, blood clots can cause a condition called deep vein thrombosis (DVT). diclo-para ineffective?" This means that the approach to diagnosis and treatment is not always the same. Complications of a swollen knee can include: Muscle loss. Blood Clot. In most cases, only one arm or leg is affected. Swelling in the leg usually begins at the foot, and then moves up if it worsens to include the ankle, calf and knee. Swelling. Leg swelling can result either from fluid build-up (fluid retention) or from inflammation in injured or diseased tissues or joints. It can appear as pain from knees to ankles, in the foot, in the knee, behind the knee, in the ankle, down the back of your leg, etc. Elevating your legs 6 to 12 inches higher than your heart whenever possible will also decrease swelling. This is one of the few edema-related causes of left leg swelling that may only affect one leg at a time. When there is leg swelling in both legs, the problem could be in the legs… Blood pooling in the legs, ankles, and feet will cause swelling. Medications, including antidepressants, some blood pressure pills, hormones and steroids are other common causes of swelling. As a result, your legs, feet, and ankles become swollen. Lymphedema causes swelling with a feeling of heaviness, tightness or fullness, usually in an arm or leg. Leg pain can affect people in any areas. Congestive heart failure can arise due to hardened arteries, damage from a heart attack, coronary heart disease, damage from infection, and similar causes. Varicose veins are another edema cause due to blood flow slowing down or blood pooling in the legs. cause increased pressure and/or leg swelling; The commonest manifestation is in the region below the knee. Your sciatic nerve runs from your lower back, through your hips and butt, and down your legs. "obese lady, 45 years, suffering from knee osteoarthritis in one leg; inability to bend knee. The swelling can make legs feel tired and heavy, and the fluid in the legs can weigh up to 10 pounds, indicates MedlinePlus. When some sort of damage causes swelling within the knee joint, the pressure pushes extra fluid in the capsule out behind the knee joint, essentially creating a what looks like a swollen … Complications. In most cases, those who have pain from their knee to ankle have lower leg pain. 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